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Target
Regulator of G-protein signaling 8
Ligand
BDBM47834
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47834
Synonyms:
2-[(4-chlorophenyl)sulfonylmethyl]-1,3-thiazole-4-carbohydrazide | 2-[(4-chlorophenyl)sulfonylmethyl]-4-thiazolecarbohydrazide | 2-[(4-chlorophenyl)sulfonylmethyl]thiazole-4-carbohydrazide | 2-{[(4-chlorophenyl)sulfonyl]methyl}-1,3-thiazole-4-carbohydrazide | MLS000859532 | SMR000461309 | cid_2743891
Type:
Small organic molecule
Emp. Form.:
C11H10ClN3O3S2
Mol. Mass.:
331.798
SMILES:
NNC(=O)c1csc(CS(=O)(=O)c2ccc(Cl)cc2)n1
Structure:
Search PDB for entries with ligand similarity: