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Target
Regulator of G-protein signaling 8
Ligand
BDBM47836
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 8
Synonyms:
RGS8 | RGS8_HUMAN | Regulator of G-protein signaling 8 (RGS8)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
20925.80
Organism:
Homo sapiens (Human)
Description:
gi_74355113
Residue:
180
Sequence:
MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALKRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLLSQSQRRLS
  
Inhibitor
Name:
BDBM47836
Synonyms:
1-N,4-N-bis[3-(1H-benzimidazol-2-yl)phenyl]benzene-1,4-dicarboxamide | MLS000766212 | N,N'-bis[3-(1H-benzimidazol-2-yl)phenyl]terephthalamide | N1,N4-bis[3-(1H-benzimidazol-2-yl)phenyl]benzene-1,4-dicarboxamide | SMR000528839 | cid_247228
Type:
Small organic molecule
Emp. Form.:
C34H24N6O2
Mol. Mass.:
548.5934
SMILES:
O=C(Nc1cccc(c1)-c1nc2ccccc2[nH]1)c1ccc(cc1)C(=O)Nc1cccc(c1)-c1nc2ccccc2[nH]1
Structure:
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