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Target
Regulator of G-protein signaling 7
Ligand
BDBM47756
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47756
Synonyms:
(4-chloro-6-methyl-pyrimidin-2-yl)amine | 4-chloranyl-6-methyl-pyrimidin-2-amine | 4-chloro-6-methyl-2-pyrimidinamine | 4-chloro-6-methylpyrimidin-2-amine | MLS000389365 | SMR000255638 | cid_21810
Type:
Small organic molecule
Emp. Form.:
C5H6ClN3
Mol. Mass.:
143.574
SMILES:
Cc1cc(Cl)nc(N)n1
Structure:
Search PDB for entries with ligand similarity: