Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 7
Ligand
BDBM47810
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 7
Synonyms:
RGS7 | RGS7_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57675.72
Organism:
Homo sapiens (Human)
Description:
P49802
Residue:
495
Sequence:
MAQGNNYGQTSNGVADESPNMLVYRKMEDVIARMQDEKNGIPIRTVKSFLSKIPSVFSGSDIVQWLIKNLTIEDPVEALHLGTLMAAHGYFFPISDHVLTLKDDGTFYRFQTPYFWPSNCWEPENTDYAVYLCKRTMQNKARLELADYEAESLARLQRAFARKWEFIFMQAEAQAKVDKKRDKIERKILDSQERAFWDVHRPVPGCVNTTEVDIKKSSRMRNPHKTRKSVYGLQNDIRSHSPTHTPTPETKPPTEDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLPPDPSNPWLSDDTTFWELEASKEPSQQRVKRWGFGMDEALKDPVGREQFLKFLESEFSSENLRFWLAVEDLKKRPIKEVPSRVQEIWQEFLAPGAPSAINLDSKSYDKTTQNVKEPGRYTFEDAQEHIYKLMKSDSYPRFIRSSAYQELLQAKKKSGNSMDRRTSFEKFAQNVGRNIPIFPCHKNCTPTLRASTNLL
  
Inhibitor
Name:
BDBM47810
Synonyms:
2-(pyridin-4-ylcarbonylamino)ethyl N-(3,4-dichlorophenyl)carbamate | 2-(pyridine-4-carbonylamino)ethyl N-(3,4-dichlorophenyl)carbamate | MLS001034017 | N-(3,4-dichlorophenyl)carbamic acid 2-[[oxo(pyridin-4-yl)methyl]amino]ethyl ester | N-(3,4-dichlorophenyl)carbamic acid 2-isonicotinamidoethyl ester | SMR000385849 | cid_2121675
Type:
Small organic molecule
Emp. Form.:
C15H13Cl2N3O3
Mol. Mass.:
354.188
SMILES:
Clc1ccc(NC(=O)OCCNC(=O)c2ccncc2)cc1Cl
Structure:
Search PDB for entries with ligand similarity: