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Target
Regulator of G-protein signaling 16
Ligand
BDBM47723
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47723
Synonyms:
(5Z)-1-(2-furanylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | (5Z)-1-(2-furfuryl)-5-[(2-thenylamino)methylene]-2-thioxo-hexahydropyrimidine-4,6-quinone | (5Z)-1-(furan-2-ylmethyl)-2-sulfanylidene-5-[(thiophen-2-ylmethylamino)methylidene]-1,3-diazinane-4,6-dione | 1-(2-furylmethyl)-5-{[(2-thienylmethyl)amino]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione | MLS000535170 | SMR000142606 | cid_5415835
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3S2
Mol. Mass.:
347.412
SMILES:
O=C1NC(=S)N(Cc2ccco2)C(=O)C1=CNCc1cccs1 |w:15.17|
Structure:
Search PDB for entries with ligand similarity: