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Target
Regulator of G-protein signaling 16
Ligand
BDBM47780
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47780
Synonyms:
2-(3,5-dimethyl-N-methylsulfonylanilino)-N-[2-(phenylmethylthio)ethyl]acetamide | 2-[(3,5-dimethylphenyl)-methylsulfonyl-amino]-N-[2-(phenylmethylsulfanyl)ethyl]ethanamide | MLS000713394 | N-(2-benzylsulfanylethyl)-2-(3,5-dimethyl-N-methylsulfonylanilino)acetamide | N-[2-(benzylthio)ethyl]-2-(N-mesyl-3,5-dimethyl-anilino)acetamide | SMR000272875 | cid_2278591
Type:
Small organic molecule
Emp. Form.:
C20H26N2O3S2
Mol. Mass.:
406.562
SMILES:
Cc1cc(C)cc(c1)N(CC(=O)NCCSCc1ccccc1)S(C)(=O)=O
Structure:
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