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Target
Regulator of G-protein signaling 16
Ligand
BDBM47784
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47784
Synonyms:
2-[[(2-acetamido-5-bromo-phenyl)-phenyl-methyl]amino]acetic acid methyl ester | 2-[[(2-acetamido-5-bromophenyl)-phenylmethyl]amino]acetic acid methyl ester | MLS000692775 | SMR000285200 | cid_2870391 | methyl 2-[[(2-acetamido-5-bromanyl-phenyl)-phenyl-methyl]amino]ethanoate | methyl 2-[[(2-acetamido-5-bromophenyl)-phenylmethyl]amino]acetate
Type:
Small organic molecule
Emp. Form.:
C18H19BrN2O3
Mol. Mass.:
391.259
SMILES:
COC(=O)CNC(c1ccccc1)c1cc(Br)ccc1NC(C)=O
Structure:
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