Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 16
Ligand
BDBM47789
Substrate
n/a
Meas. Tech.
Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao.
EC50
>30000±n/a nM
Citation
 PubChem, PC Dose respone, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao. PubChem Bioassay (2009)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47789
Synonyms:
1-(2-chloranyl-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitro-phenyl)-3-methyl-piperazine;hydrochloride | 1-(2-chloro-4-nitrophenyl)-3-methylpiperazine;hydrochloride | MLS000722903 | SMR000304898 | cid_2771392
Type:
Small organic molecule
Emp. Form.:
C11H14ClN3O2
Mol. Mass.:
255.701
SMILES:
CC1CN(CCN1)c1ccc(cc1Cl)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: