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Target
3C-like protease
Ligand
BDBM47847
Substrate
n/a
Meas. Tech.
QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro)
IC50
25347±n/a nM
Citation
 PubChem, PC QFRET-based dose response biochemical high throughput screening assay to identify inhibitors of the SARS coronavirus 3C-like Protease (3CLPro) PubChem Bioassay (2009)[AID] 
Target
Name:
3C-like protease
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
33462.05
Organism:
Avian infectious bronchitis virus
Description:
gi_73745819
Residue:
307
Sequence:
SGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVLGKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKWLESTTVSIEDYNRWASDNGFTPFSTSTAITKLSAITGVDVCKLLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQ
  
Inhibitor
Name:
BDBM47847
Synonyms:
2-(6-Fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-1-(8-methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-2-yl )-ethanone | 2-(6-fluoranyl-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanone | 2-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-1-(8-methyl-1,3,4,5-tetrahydropyrid[4,3-b]indol-2-yl)ethanone | 2-(6-fluoro-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-1-(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)ethanone | MLS000557006 | SMR000148123 | cid_4371580
Type:
Small organic molecule
Emp. Form.:
C24H26FN3O
Mol. Mass.:
391.4811
SMILES:
CC1CCc2cc(F)ccc2N1CC(=O)N1CCc2[nH]c3ccc(C)cc3c2C1
Structure:
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