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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48126
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
48600±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48126
Synonyms:
(6-chloranylimidazo[2,1-b][1,3]thiazol-5-yl)-[4-(3-chlorophenyl)piperazin-1-yl]methanone | (6-chloro-5-imidazo[2,1-b]thiazolyl)-[4-(3-chlorophenyl)-1-piperazinyl]methanone | (6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)-[4-(3-chlorophenyl)piperazin-1-yl]methanone | (6-chloroimidazo[2,1-b]thiazol-5-yl)-[4-(3-chlorophenyl)piperazino]methanone | MLS000098136 | SMR000061220 | cid_2348921
Type:
Small organic molecule
Emp. Form.:
C16H14Cl2N4OS
Mol. Mass.:
381.28
SMILES:
Clc1nc2sccn2c1C(=O)N1CCN(CC1)c1cccc(Cl)c1
Structure:
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