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Target
Matrix metalloproteinase-14 [1-36]
Ligand
BDBM48264
Substrate
n/a
Meas. Tech.
Luminescent HTS for small molecule inhibitors of MT1-MMP transcription
EC50
1980±n/a nM
Citation
 PubChem, PC Luminescent HTS for small molecule inhibitors of MT1-MMP transcription PubChem Bioassay (2008)[AID] 
Target
Name:
Matrix metalloproteinase-14 [1-36]
Synonyms:
MMP14 | MMP14_PONAB | matrix metalloproteinase 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3658.23
Organism:
Homo sapiens (Human)
Description:
gi_6690534
Residue:
36
Sequence:
MSPAPRPSRCLLLPLLTLGTALASLGSAQSSSFSPE
  
Inhibitor
Name:
BDBM48264
Synonyms:
4-methoxy-N-[2-[2-(4-methylpiperidin-1-yl)-2-oxidanylidene-ethyl]sulfanyl-4-oxidanylidene-quinazolin-3-yl]benzamide | 4-methoxy-N-[2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-4-oxoquinazolin-3-yl]benzamide | 4-methoxy-N-[2-[[2-(4-methyl-1-piperidinyl)-2-oxoethyl]thio]-4-oxo-3-quinazolinyl]benzamide | MLS000520802 | N-[4-keto-2-[[2-keto-2-(4-methylpiperidino)ethyl]thio]quinazolin-3-yl]-4-methoxy-benzamide | SMR000131211 | cid_6616230
Type:
Small organic molecule
Emp. Form.:
C24H26N4O4S
Mol. Mass.:
466.553
SMILES:
COc1ccc(cc1)C(=O)Nn1c(SCC(=O)N2CCC(C)CC2)nc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: