Reaction Details Report a problem with these data
Target
D(1A) dopamine receptor
Ligand
BDBM48909
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.0101±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM48909
Synonyms:
2-[5-(4-Fluoro-phenyl)-thiazolo[2,3-c][1,2,4]triazol-3-ylsulfanyl]-N-furan-2-ylmethyl-acetamide | 2-[[5-(4-fluorophenyl)-3-thiazolo[2,3-c][1,2,4]triazolyl]thio]-N-(2-furanylmethyl)acetamide | 2-[[5-(4-fluorophenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl]sulfanyl]-N-(furan-2-ylmethyl)acetamide | 2-[[5-(4-fluorophenyl)-[1,3]thiazolo[2,3-c][1,2,4]triazol-3-yl]sulfanyl]-N-(furan-2-ylmethyl)ethanamide | 2-[[5-(4-fluorophenyl)thiazolo[2,3-c][1,2,4]triazol-3-yl]thio]-N-(2-furfuryl)acetamide | MLS000068421 | SMR000007125 | cid_649740
Type:
Small organic molecule
Emp. Form.:
C17H13FN4O2S2
Mol. Mass.:
388.439
SMILES:
Fc1ccc(cc1)-c1csc2nnc(SCC(=O)NCc3ccco3)n12
Structure:
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