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Target
D(1A) dopamine receptor
Ligand
BDBM49095
Substrate
n/a
Meas. Tech.
Allosteric Modulators of D1 Receptors: Dose-dependent Assay
EC50
0.403±n/a nM
Citation
 PubChem, PC Allosteric Modulators of D1 Receptors: Dose-dependent Assay PubChem Bioassay (2007)[AID] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Homo sapiens (Human)
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM49095
Synonyms:
2-amino-6-ethyl-5-methyl-4-(4-pyridyl)nicotinonitrile | 2-amino-6-ethyl-5-methyl-4-pyridin-4-yl-3-pyridinecarbonitrile | 2-amino-6-ethyl-5-methyl-4-pyridin-4-ylpyridine-3-carbonitrile | 2-azanyl-6-ethyl-5-methyl-4-pyridin-4-yl-pyridine-3-carbonitrile | MLS000114815 | SMR000035572 | cid_662252
Type:
Small organic molecule
Emp. Form.:
C14H14N4
Mol. Mass.:
238.2878
SMILES:
CCc1nc(N)c(C#N)c(c1C)-c1ccncc1
Structure:
Search PDB for entries with ligand similarity: