Reaction Details Report a problem with these data
Target
dTDP-4-dehydrorhamnose 3,5-epimerase
Ligand
BDBM43035
Substrate
n/a
Meas. Tech.
Rml C and D dose-response confirmation
IC50
2761±n/a nM
Citation
 PubChem, PC Rml C and D dose-response confirmation PubChem Bioassay (2009)[AID] 
Target
Name:
dTDP-4-dehydrorhamnose 3,5-epimerase
Synonyms:
RMLC_MYCTO | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC | rmlC | strM
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22306.68
Organism:
Mycobacterium tuberculosis H37Rv
Description:
gi_15610601
Residue:
202
Sequence:
MKARELDVPGAWEITPTIHVDSRGLFFEWLTDHGFRAFAGHSLDVRQVNCSVSSAGVLRGLHFAQLPPSQAKYVTCVSGSVFDVVVDIREGSPTFGRWDSVLLDDQDRRTIYVSEGLAHGFLALQDNSTVMYLCSAEYNPQREHTICATDPTLAVDWPLVDGAAPSLSDRDAAAPSFEDVRASGLLPRWEQTQRFIGEMRGT
  
Inhibitor
Name:
BDBM43035
Synonyms:
2,3-Dihydro-benzo[1,4]dioxine-6-carboxylic acid (2-naphthalen-2-yl-benzooxazol-5-yl)-amide | MLS000558441 | N-(2-naphthalen-2-yl-1,3-benzoxazol-5-yl)-2,3-dihydro-1,4-benzodioxine-6-carboxamide | N-[2-(2-naphthalenyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | N-[2-(2-naphthyl)-1,3-benzoxazol-5-yl]-2,3-dihydro-1,4-benzodioxin-6-carboxamide | SMR000148957 | cid_4378441
Type:
Small organic molecule
Emp. Form.:
C26H18N2O4
Mol. Mass.:
422.4321
SMILES:
O=C(Nc1ccc2oc(nc2c1)-c1ccc2ccccc2c1)c1ccc2OCCOc2c1
Structure:
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