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Target
Beta-lactamase
Ligand
BDBM51959
Substrate
n/a
Meas. Tech.
Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
IC50
59640±n/a nM
Citation
 PubChem, PC Epi-absorbance-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM51959
Synonyms:
4-butyl-3-(2-methyl-3-furanyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(2-methyl-3-furyl)-1H-1,2,4-triazole-5-thione | 4-butyl-3-(2-methylfuran-3-yl)-1H-1,2,4-triazole-5-thione | 4-butyl-5-(2-methyl-3-furyl)-4H-1,2,4-triazole-3-thiol | MLS000547853 | SMR000115049 | cid_1768039
Type:
Small organic molecule
Emp. Form.:
C11H15N3OS
Mol. Mass.:
237.321
SMILES:
CCCCn1c(n[nH]c1=S)-c1ccoc1C
Structure:
Search PDB for entries with ligand similarity: