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Target
Beta-lactamase
Ligand
BDBM51990
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
8569±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM51990
Synonyms:
3-(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)-1-phenyl-4(1H)-pyridazinone | 3-(4-ethyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)-1-phenyl-4-pyridazinone | 3-(4-ethyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)-1-phenyl-pyridazin-4-one | 3-(4-ethyl-5-sulfanylidene-1H-1,2,4-triazol-3-yl)-1-phenylpyridazin-4-one | 3-(4-ethyl-5-thioxo-1H-1,2,4-triazol-3-yl)-1-phenyl-pyridazin-4-one | MLS000763629 | SMR000337209 | cid_1481298
Type:
Small organic molecule
Emp. Form.:
C14H13N5OS
Mol. Mass.:
299.351
SMILES:
CCn1c(n[nH]c1=S)-c1nn(ccc1=O)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: