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Target
Beta-lactamase
Ligand
BDBM52026
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase.
IC50
59640±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify inhibitors of IMP-1 metallo-beta-lactamase. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase | metallo-beta-lactamase IMP-1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
27125.88
Organism:
Pseudomonas aeruginosa
Description:
gi_27368096
Residue:
246
Sequence:
MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNAEAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELTNELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKPYGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKKPSKPSN
  
Inhibitor
Name:
BDBM52026
Synonyms:
2-(1-naphthoyl)benzoic acid | 2-(naphthalene-1-carbonyl)benzoic acid | 2-[1-naphthalenyl(oxo)methyl]benzoic acid | 2-naphthalen-1-ylcarbonylbenzoic acid | MLS001195141 | SMR000554507 | cid_78723
Type:
Small organic molecule
Emp. Form.:
C18H12O3
Mol. Mass.:
276.2861
SMILES:
OC(=O)c1ccccc1C(=O)c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: