Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52132
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52132
Synonyms:
(5E)-5-[[4-(4-acetyl-1-piperazinyl)anilino]methylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | (5E)-5-[[4-(4-acetylpiperazin-1-yl)anilino]methylidene]-1-benzyl-1,3-diazinane-2,4,6-trione | (5E)-5-[[4-(4-acetylpiperazino)anilino]methylene]-1-benzyl-barbituric acid | (5E)-5-[[[4-(4-ethanoylpiperazin-1-yl)phenyl]amino]methylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | MLS000041641 | SMR000045995 | cid_5389908
Type:
Small organic molecule
Emp. Form.:
C24H25N5O4
Mol. Mass.:
447.4864
SMILES:
CC(=O)N1CCN(CC1)c1ccc(NC=C2C(=O)NC(=O)N(Cc3ccccc3)C2=O)cc1 |w:14.14|
Structure:
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