Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52202
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52202
Synonyms:
2-amino-5-keto-7,7-dimethyl-4-(2,3,4-trimethoxyphenyl)-6,8-dihydro-4H-chromene-3-carbonitrile | 2-amino-7,7-dimethyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-6,8-dihydro-4H-1-benzopyran-3-carbonitrile | 2-amino-7,7-dimethyl-5-oxo-4-(2,3,4-trimethoxyphenyl)-6,8-dihydro-4H-chromene-3-carbonitrile | 2-azanyl-7,7-dimethyl-5-oxidanylidene-4-(2,3,4-trimethoxyphenyl)-6,8-dihydro-4H-chromene-3-carbonitrile | MLS000104772 | SMR000054705 | cid_2828669
Type:
Small organic molecule
Emp. Form.:
C21H24N2O5
Mol. Mass.:
384.4257
SMILES:
COc1ccc(C2C(C#N)C(=N)OC3=C2C(=O)CC(C)(C)C3)c(OC)c1OC |c:13|
Structure:
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