Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52224
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52224
Synonyms:
MLS000523368 | N-(5,8-Dimethyl-2-oxo-1,2-dihydro-quinolin-3-ylmethyl)-4-methyl-N-[3-(2-oxo-pyrrolidin-1-yl)-propyl]-benzenesulfonamide | N-[(2-keto-5,8-dimethyl-1H-quinolin-3-yl)methyl]-N-[3-(2-ketopyrrolidino)propyl]-4-methyl-benzenesulfonamide | N-[(5,8-dimethyl-2-oxidanylidene-1H-quinolin-3-yl)methyl]-4-methyl-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]benzenesulfonamide | N-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-4-methyl-N-[3-(2-oxo-1-pyrrolidinyl)propyl]benzenesulfonamide | N-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]-4-methyl-N-[3-(2-oxopyrrolidin-1-yl)propyl]benzenesulfonamide | SMR000123346 | cid_3203401
Type:
Small organic molecule
Emp. Form.:
C26H31N3O4S
Mol. Mass.:
481.607
SMILES:
Cc1ccc(cc1)S(=O)(=O)N(CCCN1CCCC1=O)Cc1cc2c(C)ccc(C)c2[nH]c1=O
Structure:
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