Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52266
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52266
Synonyms:
4-[[(E)-(2-ketocyclohexylidene)methyl]amino]benzoic acid ethyl ester | 4-[[(E)-(2-oxocyclohexylidene)methyl]amino]benzoic acid ethyl ester | MLS000532541 | SMR000137480 | cid_781824 | ethyl 4-[[(E)-(2-oxidanylidenecyclohexylidene)methyl]amino]benzoate | ethyl 4-[[(E)-(2-oxocyclohexylidene)methyl]amino]benzoate | ethyl 4-{[(2-oxocyclohexylidene)methyl]amino}benzoate
Type:
Small organic molecule
Emp. Form.:
C16H19NO3
Mol. Mass.:
273.327
SMILES:
CCOC(=O)c1ccc(NC=C2CCCCC2=O)cc1 |w:10.9|
Structure:
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