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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM53583
Substrate
n/a
Meas. Tech.
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50
100000±n/a nM
Citation
 PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM53583
Synonyms:
1-hydroxy-2,2-dimethyl-3-oxido-4-(2-thienyl)-3-imidazolin-3-ium | 2,2-dimethyl-1-oxidanidyl-3-oxidanyl-5-thiophen-2-yl-4H-imidazol-1-ium | 3-hydroxy-2,2-dimethyl-1-oxido-5-thiophen-2-yl-4H-imidazol-1-ium | MLS000106712 | SMR000111088 | cid_871986
Type:
Small organic molecule
Emp. Form.:
C9H12N2O2S
Mol. Mass.:
212.269
SMILES:
CC1(C)N(O)CC(c2cccs2)=[N+]1[O-] |c:12|
Structure:
Search PDB for entries with ligand similarity: