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Target
Mannose-6-phosphate isomerase
Ligand
BDBM53602
Substrate
n/a
Meas. Tech.
HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay.
IC50
50000±n/a nM
Citation
 PubChem, PC HTS identification of compounds inhibiting phosphomannose isomerase (PMI) via a fluorescence intensity assay. PubChem Bioassay (2009)[AID] 
Target
Name:
Mannose-6-phosphate isomerase
Synonyms:
MPI | MPI protein | MPI_HUMAN | Mannose-6-phosphate isomerase | PMI1
Type:
PROTEIN
Mol. Mass.:
46651.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1448919
Residue:
423
Sequence:
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEMAIALTPFQGLCGFRPVEEIVTFLKKVPEFQFLIGDEAATHLKQTMSHDSQAVASSLQSCFSHLMKSEKKVVVEQLNLLVKRISQQAAAGNNMEDIFGELLLQLHQQYPGDIGCFAIYFLNLLTLKPGEAMFLEANVPHAYLKGDCVECMACSDNTVRAGLTPKFIDVPTLCEMLSYTPSSSKDRLFLPTRSQEDPYLSIYDPPVPDFTIMKTEVPGSVTEYKVLALDSASILLMVQGTVIASTPTTQTPIPLQRGGVLFIGANESVSLKLTEPKDLLIFRACCLL
  
Inhibitor
Name:
BDBM53602
Synonyms:
MLS000547243 | N-[(7-methyl-8-quinolyl)thiocarbamoyl]benzamide | N-[(7-methylquinolin-8-yl)carbamothioyl]benzamide | N-[[(7-methyl-8-quinolinyl)amino]-sulfanylidenemethyl]benzamide | N-benzoyl-N'-(7-methyl-8-quinolinyl)thiourea | SMR000180341 | cid_3477730
Type:
Small organic molecule
Emp. Form.:
C18H15N3OS
Mol. Mass.:
321.396
SMILES:
Cc1ccc2cccnc2c1NC(=S)NC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: