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Target
M1 family aminopeptidase
Ligand
BDBM54144
Substrate
n/a
Meas. Tech.
Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP)
IC50
17130±n/a nM
Citation
 PubChem, PC Inhibitors of Plasmodium falciparum M1- Family Alanyl Aminopeptidase (M1AAP) PubChem Bioassay (2008)[AID] 
Target
Name:
M1 family aminopeptidase
Synonyms:
AMPN_PLAF7 | M1AAP | Zinc aminopeptidase | m1-family aminopeptidase
Type:
PROTEIN
Mol. Mass.:
126072.31
Organism:
Plasmodium falciparum (isolate FcB1 / Columbia)
Description:
ChEMBL_735637
Residue:
1085
Sequence:
MKLTKGCAYKYIIFTVLILANILYDNKKRCMIKKNLRISSCGIISRLLKSNSNYNSFNKNYNFTSAISELQFSNFWNLDILQKDIFSNIHNNKNKPQSYIIHKRLMSEKGDNNNNNHQNNNGNDNKKRLGSVVNNEENTCSDKRMKPFEEGHGITQVDKMNNNSDHLQQNGVMNLNSNNVENNNNNNSVVVKKNEPKIHYRKDYKPSGFIINNVTLNINIHDNETIVRSVLDMDISKHNVGEDLVFDGVGLKINEISINNKKLVEGEEYTYDNEFLTIFSKFVPKSKFAFSSEVIIHPETNYALTGLYKSKNIIVSQCEATGFRRITFFIDRPDMMAKYDVTVTADKEKYPVLLSNGDKVNEFEIPGGRHGARFNDPHLKPCYLFAVVAGDLKHLSATYITKYTKKKVELYVFSEEKYVSKLQWALECLKKSMAFDEDYFGLEYDLSRLNLVAVSDFNVGAMENKGLNIFNANSLLASKKNSIDFSYARILTVVGHEYFHNYTGNRVTLRDWFQLTLKEGLTVHRENLFSEEMTKTVTTRLSHVDLLRSVQFLEDSSPLSHPIRPESYVSMENFYTTTVYDKGSEVMRMYLTILGEEYYKKGFDIYIKKNDGNTATCEDFNYAMEQAYKMKKADNSANLNQYLLWFSQSGTPHVSFKYNYDAEKKQYSIHVNQYTKPDENQKEKKPLFIPISVGLINPENGKEMISQTTLELTKESDTFVFNNIAVKPIPSLFRGFSAPVYIEDNLTDEERILLLKYDSDAFVRYNSCTNIYMKQILMNYNEFLKAKNEKLESFNLTPVNAQFIDAIKYLLEDPHADAGFKSYIVSLPQDRYIINFVSNLDTDVLADTKEYIYKQIGDKLNDVYYKMFKSLEAKADDLTYFNDESHVDFDQMNMRTLRNTLLSLLSKAQYPNILNEIIEHSKSPYPSNWLTSLSVSAYFDKYFELYDKTYKLSKDDELLLQEWLKTVSRSDRKDIYEILKKLENEVLKDSKNPNDIRAVYLPFTNNLRRFHDISGKGYKLIAEVITKTDKFNPMVATQLCEPFKLWNKLDTKRQELMLNEMNTMLQEPNISNNLKEYLLRLTNKL
  
Inhibitor
Name:
BDBM54144
Synonyms:
2-(2-{[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thienyl]amino}-2-oxoethoxy)acetic acid | 2-[2-[[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thienyl]amino]-2-keto-ethoxy]acetic acid | 2-[2-[[3-(1,3-benzothiazol-2-yl)-4-methyl-2-thiophenyl]amino]-2-oxoethoxy]acetic acid | 2-[2-[[3-(1,3-benzothiazol-2-yl)-4-methyl-thiophen-2-yl]amino]-2-oxidanylidene-ethoxy]ethanoic acid | 2-[2-[[3-(1,3-benzothiazol-2-yl)-4-methylthiophen-2-yl]amino]-2-oxoethoxy]acetic acid | MLS000850220 | SMR000456238 | cid_2811899
Type:
Small organic molecule
Emp. Form.:
C16H14N2O4S2
Mol. Mass.:
362.423
SMILES:
Cc1csc(NC(=O)COCC(O)=O)c1-c1nc2ccccc2s1
Structure:
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