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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM42216
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1120±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM42216
Synonyms:
3-(4-fluoroanilino)-2H-isoquinolin-1-one | 3-(4-fluoroanilino)isocarbostyril | 3-[(4-fluorophenyl)amino]-2H-isoquinolin-1-one | MLS000565365 | SMR000152650 | cid_2323972
Type:
Small organic molecule
Emp. Form.:
C15H11FN2O
Mol. Mass.:
254.259
SMILES:
Fc1ccc(Nc2cc3ccccc3c(=O)[nH]2)cc1
Structure:
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