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Target
Ras-related C3 botulinum toxin substrate 1
Ligand
BDBM54546
Substrate
n/a
Meas. Tech.
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype
EC50
3793±n/a nM
Citation
 PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rac1 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related C3 botulinum toxin substrate 1
Synonyms:
RAC1_MOUSE | Rac1 | Rac1 protein
Type:
PROTEIN
Mol. Mass.:
21455.91
Organism:
Mus musculus
Description:
EBI_101485
Residue:
192
Sequence:
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL
  
Inhibitor
Name:
BDBM54546
Synonyms:
1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-butanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one | 1-[4-(2,5-dimethylphenyl)piperazino]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one | KUC103353N | UNM-0000306067 | cid_25241703
Type:
Small organic molecule
Emp. Form.:
C25H30N4O3
Mol. Mass.:
434.5307
SMILES:
COc1ccc(cc1)-c1noc(CCCC(=O)N2CCN(CC2)c2cc(C)ccc2C)n1
Structure:
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