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Target
Streptokinase A
Ligand
BDBM54848
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
8369±1172 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54848
Synonyms:
BRD-A72194916-001-04-6 | N,N-diethylcarbamodithioic acid [1-(5-bromo-2-hydroxyphenyl)-1-oxopropan-2-yl] ester | N,N-diethylcarbamodithioic acid [2-(5-bromo-2-hydroxy-phenyl)-2-keto-1-methyl-ethyl] ester | [1-(5-bromanyl-2-oxidanyl-phenyl)-1-oxidanylidene-propan-2-yl] N,N-diethylcarbamodithioate | [1-(5-bromo-2-hydroxyphenyl)-1-oxopropan-2-yl] N,N-diethylcarbamodithioate | cid_5244453
Type:
Small organic molecule
Emp. Form.:
C14H18BrNO2S2
Mol. Mass.:
376.332
SMILES:
CCN(CC)C(=S)SC(C)C(=O)c1cc(Br)ccc1O
Structure:
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