Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54974
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54974
Synonyms:
5-(cyclopropanecarbonylthiocarbamoylamino)-3-methyl-thiophene-2-carboxylic acid ethyl ester | 5-[[[[cyclopropyl(oxo)methyl]amino]-sulfanylidenemethyl]amino]-3-methyl-2-thiophenecarboxylic acid ethyl ester | MLS000392602 | SMR000261507 | cid_2373848 | ethyl 5-(cyclopropanecarbonylcarbamothioylamino)-3-methylthiophene-2-carboxylate | ethyl 5-(cyclopropylcarbonylcarbamothioylamino)-3-methyl-thiophene-2-carboxylate
Type:
Small organic molecule
Emp. Form.:
C13H16N2O3S2
Mol. Mass.:
312.408
SMILES:
CCOC(=O)c1sc(NC(=S)NC(=O)C2CC2)cc1C
Structure:
Search PDB for entries with ligand similarity: