Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM55000
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
16734±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM55000
Synonyms:
(E)-N-[2-(2,6-difluoroanilino)-2-keto-ethyl]-N-ethyl-3-(2-quinolyl)acrylamide | (E)-N-[2-(2,6-difluoroanilino)-2-oxoethyl]-N-ethyl-3-(2-quinolinyl)-2-propenamide | (E)-N-[2-(2,6-difluoroanilino)-2-oxoethyl]-N-ethyl-3-quinolin-2-ylprop-2-enamide | (E)-N-[2-[[2,6-bis(fluoranyl)phenyl]amino]-2-oxidanylidene-ethyl]-N-ethyl-3-quinolin-2-yl-prop-2-enamide | MLS001128172 | SMR000713765 | cid_24979772
Type:
Small organic molecule
Emp. Form.:
C22H19F2N3O2
Mol. Mass.:
395.402
SMILES:
CCN(CC(=O)Nc1c(F)cccc1F)C(=O)\C=C\c1ccc2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: