Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM50637
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
680±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM50637
Synonyms:
1,4-bis(azanyl)-2,3-dihydroanthracene-9,10-dione | 1,4-diamino-2,3-dihydroanthracene-9,10-dione | 1,4-diamino-2,3-dihydroanthracene-9,10-quinone | MLS000738012 | SMR000393688 | cid_5354979
Type:
Small organic molecule
Emp. Form.:
C14H12N2O2
Mol. Mass.:
240.2573
SMILES:
Nc1ccc(N)c2c(O)c3ccccc3c(O)c12
Structure:
Search PDB for entries with ligand similarity: