Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM56839
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
42500±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM56839
Synonyms:
2-(1,3-diketo-3a,4,7,7a-tetrahydroisoindol-2-yl)-N-thiazol-2-yl-acetamide | 2-(1,3-dioxo-3a,4,7,7a-tetrahydroisoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide | 2-(1,3-dioxo-3a,4,7,7a-tetrahydroisoindol-2-yl)-N-(2-thiazolyl)acetamide | 2-[1,3-bis(oxidanylidene)-3a,4,7,7a-tetrahydroisoindol-2-yl]-N-(1,3-thiazol-2-yl)ethanamide | MLS000054855 | SMR000066792 | cid_2999923
Type:
Small organic molecule
Emp. Form.:
C13H13N3O3S
Mol. Mass.:
291.326
SMILES:
O=C(CN1C(=O)C2CC=CCC2C1=O)Nc1nccs1 |c:8|
Structure:
Search PDB for entries with ligand similarity: