Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM56849
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
85000±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM56849
Synonyms:
MLS000052557 | N-[3-[2-(4-methylphenyl)-2-oxidanylidene-ethoxy]phenyl]furan-2-carboxamide | N-[3-[2-(4-methylphenyl)-2-oxoethoxy]phenyl]-2-furancarboxamide | N-[3-[2-(4-methylphenyl)-2-oxoethoxy]phenyl]furan-2-carboxamide | N-[3-[2-keto-2-(p-tolyl)ethoxy]phenyl]-2-furamide | N-{3-[2-(4-methylphenyl)-2-oxoethoxy]phenyl}-2-furamide | SMR000082052 | cid_1218909
Type:
Small organic molecule
Emp. Form.:
C20H17NO4
Mol. Mass.:
335.3533
SMILES:
Cc1ccc(cc1)C(=O)COc1cccc(NC(=O)c2ccco2)c1
Structure:
Search PDB for entries with ligand similarity: