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Target
Streptokinase A
Ligand
BDBM58086
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58086
Synonyms:
MLS000806923 | SMR000414723 | Tricyclo[4.3.1.1*3,8*]undecane-1-carboxylic acid [1-(3-bromo-2-hydroxy-5-nitro-phenyl)-meth-(E)-ylidene]-hydrazide | cid_6291459
Type:
Small organic molecule
Emp. Form.:
C19H22BrN3O4
Mol. Mass.:
436.3
SMILES:
[H]C12CC3([H])CC(C1)(CC([H])(C2)CC3)C(=O)NN\C=C1/C=C(C=C(Br)C1=O)[N+]([O-])=O |c:23,t:25,TLB:12:9:7:3.5.2,THB:2:1:8:3.5.12.13,2:3:8:1.7.11,13:3:7:9.8.11|
Structure:
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