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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM59341
Substrate
n/a
Meas. Tech.
Chemical Antagonists IAP-family anti-apoptotic proteins
IC50
100000±n/a nM
Citation
 PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay (2008)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM59341
Synonyms:
3-[(Benzyl-{1-[1-(2-methoxy-ethyl)-1H-tetrazol-5-yl]-2-methyl-propyl}-amino)-methyl]-6-methoxy-1H-quinolin-2-one | 3-[[benzyl-[1-[1-(2-methoxyethyl)tetrazol-5-yl]-2-methyl-propyl]amino]methyl]-6-methoxy-carbostyril | 3-[[benzyl-[1-[1-(2-methoxyethyl)tetrazol-5-yl]-2-methylpropyl]amino]methyl]-6-methoxy-1H-quinolin-2-one | 6-methoxy-3-[[[1-[1-(2-methoxyethyl)-1,2,3,4-tetrazol-5-yl]-2-methyl-propyl]-(phenylmethyl)amino]methyl]-1H-quinolin-2-one | 6-methoxy-3-[[[1-[1-(2-methoxyethyl)-5-tetrazolyl]-2-methylpropyl]-(phenylmethyl)amino]methyl]-1H-quinolin-2-one | MLS000031133 | SMR000004515 | cid_656364
Type:
Small organic molecule
Emp. Form.:
C26H32N6O3
Mol. Mass.:
476.5707
SMILES:
COCCn1nnnc1C(C(C)C)N(Cc1ccccc1)Cc1cc2cc(OC)ccc2[nH]c1=O
Structure:
Search PDB for entries with ligand similarity: