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Target
G-protein coupled receptor 35
Ligand
BDBM61615
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
4956.042±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61615
Synonyms:
MLS000722217 | N-[4-[(E)-3-(2-furanyl)-1-oxoprop-2-enyl]phenyl]-1-adamantanecarboxamide | N-[4-[(E)-3-(2-furyl)acryloyl]phenyl]adamantane-1-carboxamide | N-[4-[(E)-3-(furan-2-yl)prop-2-enoyl]phenyl]adamantane-1-carboxamide | SMR000235859 | cid_7424594
Type:
Small organic molecule
Emp. Form.:
C24H25NO3
Mol. Mass.:
375.4602
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)C(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccco1 |TLB:8:1:12:6.9.5,8:6:12:1.11.2,THB:2:1:9:3.12.5|
Structure:
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