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Target
G-protein coupled receptor 35
Ligand
BDBM61625
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
8800.735±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61625
Synonyms:
2-chloranyl-N-[2-[(2-chloranylpyridin-3-yl)carbonylamino]-4-(diethylsulfamoyl)phenyl]pyridine-3-carboxamide | 2-chloro-N-[2-[(2-chloronicotinoyl)amino]-4-(diethylsulfamoyl)phenyl]nicotinamide | 2-chloro-N-[2-[(2-chloropyridine-3-carbonyl)amino]-4-(diethylsulfamoyl)phenyl]pyridine-3-carboxamide | 2-chloro-N-[2-[[(2-chloro-3-pyridinyl)-oxomethyl]amino]-4-(diethylsulfamoyl)phenyl]-3-pyridinecarboxamide | MLS000775827 | SMR000370947 | cid_3276705
Type:
Small organic molecule
Emp. Form.:
C22H21Cl2N5O4S
Mol. Mass.:
522.404
SMILES:
CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cccnc2Cl)c(NC(=O)c2cccnc2Cl)c1
Structure:
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