Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM58342
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
701.4876±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM58342
Synonyms:
(5E)-5-[4-(4-ethoxy-N-methyl-anilino)benzylidene]-2-thioxo-thiazolidin-4-one | (5E)-5-[[4-(4-ethoxy-N-methylanilino)phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | (5E)-5-[[4-(4-ethoxy-N-methylanilino)phenyl]methylidene]-2-sulfanylidene-4-thiazolidinone | (5E)-5-[[4-[(4-ethoxyphenyl)-methyl-amino]phenyl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one | 5-{4-[(4-Ethoxy-phenyl)-methyl-amino]-benzylidene}-2-thioxo-thiazolidin-4-one | MLS001212597 | SMR000518479 | cid_5767616
Type:
Small organic molecule
Emp. Form.:
C19H18N2O2S2
Mol. Mass.:
370.488
SMILES:
CCOc1ccc(cc1)N(C)c1ccc(C=C2SC(S)=NC2=O)cc1 |w:15.15,c:20|
Structure:
Search PDB for entries with ligand similarity: