Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61593
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
3542.33±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61593
Synonyms:
5-[4-(dimethylamino)phenyl]-N-(2-methoxy-5-methyl-phenyl)-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride | 5-[4-(dimethylamino)phenyl]-N-(2-methoxy-5-methylphenyl)-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride | MLS000948484 | SMR000526900 | [4-[5-(2-methoxy-5-methyl-anilino)-3-phenyl-1,3,4-thiadiazol-3-ium-2-yl]phenyl]-dimethyl-amine;chloride | cid_24792181
Type:
Small organic molecule
Emp. Form.:
C24H25N4OS
Mol. Mass.:
417.546
SMILES:
COc1ccc(C)cc1Nc1n[n+](c(s1)-c1ccc(cc1)N(C)C)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: