Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM61786
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM61786
Synonyms:
MLS000714627 | N-tert-butyl-2-(2-fluoro-N-[2-[5-(4-fluorophenyl)-2-tetrazolyl]-1-oxoethyl]anilino)-2-(4-hydroxyphenyl)acetamide | N-tert-butyl-2-(2-fluoro-N-[2-[5-(4-fluorophenyl)tetrazol-2-yl]acetyl]anilino)-2-(4-hydroxyphenyl)acetamide | N-tert-butyl-2-[(2-fluorophenyl)-[2-[5-(4-fluorophenyl)-1,2,3,4-tetrazol-2-yl]ethanoyl]amino]-2-(4-hydroxyphenyl)ethanamide | SMR000274606 | cid_3178985
Type:
Small organic molecule
Emp. Form.:
C27H26F2N6O3
Mol. Mass.:
520.5305
SMILES:
CC(C)(C)NC(=O)C(N(C(=O)Cn1nnc(n1)-c1ccc(F)cc1)c1ccccc1F)c1ccc(O)cc1
Structure:
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