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Target
Neuropeptide Y receptor type 2
Ligand
BDBM61835
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
11337±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61835
Synonyms:
MLS001003888 | N-[(6-fluoranyl-2,3-dihydrothiochromen-4-ylidene)amino]pyridin-2-amine | N-[(6-fluoro-2,3-dihydro-1-benzothiopyran-4-ylidene)amino]-2-pyridinamine | N-[(6-fluoro-2,3-dihydrothiochromen-4-ylidene)amino]pyridin-2-amine | SMR000377665 | [(6-fluorothiochroman-4-ylidene)amino]-(2-pyridyl)amine | cid_3355664
Type:
Small organic molecule
Emp. Form.:
C14H12FN3S
Mol. Mass.:
273.329
SMILES:
Fc1ccc2SCCC(=NNc3ccccn3)c2c1 |w:9.9|
Structure:
Search PDB for entries with ligand similarity: