Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM54136
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.
EC50
>11810±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM54136
Synonyms:
2-[[(Z)-[1,3-diketo-2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-4-isoquinolylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-bis(oxidanylidene)isoquinolin-4-ylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-dioxo-4-isoquinolinylidene]methyl]amino]benzoic acid | 2-[[(Z)-[2-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]-1,3-dioxoisoquinolin-4-ylidene]methyl]amino]benzoic acid | MLS000776209 | SMR000371212 | cid_6163965
Type:
Small organic molecule
Emp. Form.:
C30H23N3O7S
Mol. Mass.:
569.585
SMILES:
COc1ccccc1NS(=O)(=O)c1cccc(c1)-n1c(O)c(C=Nc2ccccc2C(O)=O)c2ccccc2c1=O |w:23.25|
Structure:
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