Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM61781
Substrate
n/a
Meas. Tech.
Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
35430±n/a nM
Citation
 PubChem, PC Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM61781
Synonyms:
(4-benzhydrylpiperazin-1-yl)-[5-(3-hydroxyphenyl)-1,2-oxazol-3-yl]methanone | (4-benzhydrylpiperazino)-[5-(3-hydroxyphenyl)isoxazol-3-yl]methanone | MLS000116285 | SMR000093262 | [4-(diphenylmethyl)-1-piperazinyl]-[5-(3-hydroxyphenyl)-3-isoxazolyl]methanone | [4-(diphenylmethyl)piperazin-1-yl]-[5-(3-hydroxyphenyl)-1,2-oxazol-3-yl]methanone | cid_5309420
Type:
Small organic molecule
Emp. Form.:
C27H25N3O3
Mol. Mass.:
439.5057
SMILES:
Oc1cccc(c1)-c1cc(no1)C(=O)N1CCN(CC1)C(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: