Reaction Details Report a problem with these data
Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62108
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62108
Synonyms:
MLS000733540 | N-butyl-3-[[4-[(E)-cinnamyl]piperazino]methyl]-N-methyl-imidazo[1,2-a]pyridine-2-carboxamide | N-butyl-N-methyl-3-({4-[(2E)-3-phenylprop-2-en-1-yl]piperazin-1-yl}methyl)imidazo[1,2-a]pyridine-2-carboxamide | N-butyl-N-methyl-3-[[4-[(E)-3-phenylprop-2-enyl]-1-piperazinyl]methyl]-2-imidazo[1,2-a]pyridinecarboxamide | N-butyl-N-methyl-3-[[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methyl]imidazo[1,2-a]pyridine-2-carboxamide | SMR000317763 | cid_16190353
Type:
Small organic molecule
Emp. Form.:
C27H35N5O
Mol. Mass.:
445.5997
SMILES:
CCCCN(C)C(=O)c1nc2ccccn2c1CN1CCN(C\C=C\c2ccccc2)CC1
Structure:
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