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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62123
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
43807±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62123
Synonyms:
5-bromanyl-1-[(6-methylquinolin-8-yl)methyl]pyridin-1-ium-2-amine;bromide | 5-bromo-1-[(6-methyl-8-quinolinyl)methyl]-2-pyridin-1-iumamine;bromide | 5-bromo-1-[(6-methylquinolin-8-yl)methyl]pyridin-1-ium-2-amine;bromide | MLS001013428 | SMR000353420 | [5-bromo-1-[(6-methyl-8-quinolyl)methyl]pyridin-1-ium-2-yl]amine;bromide | cid_16196242
Type:
Small organic molecule
Emp. Form.:
C16H15BrN3
Mol. Mass.:
329.214
SMILES:
Cc1cc(Cn2cc(Br)ccc2=[NH2+])c2ncccc2c1
Structure:
Search PDB for entries with ligand similarity: