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Target
Neuropeptides B/W receptor type 1
Ligand
BDBM62162
Substrate
n/a
Meas. Tech.
Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7).
IC50
34598±n/a nM
Citation
 PubChem, PC Fluorescence-based dose response cell-based high throughput screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7). PubChem Bioassay (2010)[AID] 
Target
Name:
Neuropeptides B/W receptor type 1
Synonyms:
GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36111.82
Organism:
Homo sapiens (Human)
Description:
gi_119607128
Residue:
328
Sequence:
MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLYVLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLDDEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAKALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANSCLNPFLYAFLDASFRRNLRQLITCRAAA
  
Inhibitor
Name:
BDBM62162
Synonyms:
MLS001073551 | SMR000654397 | [3-(2,4-difluorobenzyl)-3-methylol-piperidino]-(5-isobutyl-1H-pyrazol-3-yl)methanone | [3-[(2,4-difluorophenyl)methyl]-3-(hydroxymethyl)-1-piperidinyl]-[5-(2-methylpropyl)-1H-pyrazol-3-yl]methanone | [3-[(2,4-difluorophenyl)methyl]-3-(hydroxymethyl)piperidin-1-yl]-[5-(2-methylpropyl)-1H-pyrazol-3-yl]methanone | [3-[[2,4-bis(fluoranyl)phenyl]methyl]-3-(hydroxymethyl)piperidin-1-yl]-[5-(2-methylpropyl)-1H-pyrazol-3-yl]methanone | cid_24794275
Type:
Small organic molecule
Emp. Form.:
C21H27F2N3O2
Mol. Mass.:
391.4548
SMILES:
CC(C)Cc1cc([nH]n1)C(=O)N1CCCC(CO)(Cc2ccc(F)cc2F)C1
Structure:
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