Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM38361
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds
Ki
270±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS4-Galphao for SAR compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM38361
Synonyms:
2-(4-pyrrolidin-1-ylsulfonylphenyl)-1,2-benzothiazol-3-one | 2-(4-pyrrolidinosulfonylphenyl)-1,2-benzothiazol-3-one | 2-[4-(1-pyrrolidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one | MLS000055723 | SMR000060746 | cid_2325816
Type:
Small organic molecule
Emp. Form.:
C17H16N2O3S2
Mol. Mass.:
360.451
SMILES:
O=c1n(sc2ccccc12)-c1ccc(cc1)S(=O)(=O)N1CCCC1
Structure:
Search PDB for entries with ligand similarity: