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Target
Regulator of G-protein signaling 16
Ligand
BDBM47719
Substrate
n/a
Meas. Tech.
Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds
Ki
40±n/a nM
Citation
 PubChem, PC Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS16-Galphao for SAR Compounds PubChem Bioassay (2010)[AID] 
Target
Name:
Regulator of G-protein signaling 16
Synonyms:
RGS16 | RGS16_HUMAN | RGSR | Regulator of G-protein signaling 16 (RGS16) | regulator of G-protein signalling 16
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22748.87
Organism:
Homo sapiens (Human)
Description:
gi_156416009
Residue:
202
Sequence:
MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEEFICSEAPKEVNIDHETHELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASAASATLSSCSLDEPSHT
  
Inhibitor
Name:
BDBM47719
Synonyms:
(4-chlorodithiazol-5-ylidene)-(4-chloro-2-methyl-phenyl)amine | 4-chloranyl-N-(4-chloranyl-2-methyl-phenyl)-1,2,3-dithiazol-5-imine | 4-chloro-N-(4-chloro-2-methylphenyl)-5-dithiazolimine | 4-chloro-N-(4-chloro-2-methylphenyl)dithiazol-5-imine | 4-chloro-N-(4-chloro-5H-1,2,3-dithiazol-5-yliden)-2-methylaniline | MLS000539990 | SMR000125448 | cid_1471255
Type:
Small organic molecule
Emp. Form.:
C9H6Cl2N2S2
Mol. Mass.:
277.193
SMILES:
Cc1cc(Cl)ccc1\N=c1\ssnc1Cl
Structure:
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