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Target
Serine/threonine-protein phosphatase
Ligand
BDBM64799
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5)
IC50
7450±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of Protein Phosphatase 5 (PP5) PubChem Bioassay (2010)[AID] 
Target
Name:
Serine/threonine-protein phosphatase
Synonyms:
H0YDU8_HUMAN | PPP5C | PPP5C protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55092.68
Organism:
Homo sapiens (Human)
Description:
gi_37589898
Residue:
484
Sequence:
MAEGERTECAEPPRDEPPADGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAIAGDEHKRSVVDSLDIESMTIEDEYSGPKLEDGKVTISFMKELMQWYKDQKKLHRKCAYQILVQVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVGRPSSGS
  
Inhibitor
Name:
BDBM64799
Synonyms:
(4aS)-2,4a,9-trimethyl-2,3,4,4a,9,9a-hexahydro-[1,2]oxazino[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-[1,2]oxazino[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazin[6,5-b]indol-6-ol | (4aS)-2,4a,9-trimethyl-4,9a-dihydro-3H-oxazino[6,5-b]indol-6-ol | MLS001060820 | SMR000486281 | cid_24747147
Type:
Small organic molecule
Emp. Form.:
C13H18N2O2
Mol. Mass.:
234.2942
SMILES:
CN1C2ON(C)CC[C@@]2(C)c2cc(O)ccc12
Structure:
Search PDB for entries with ligand similarity: