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Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM61963
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM61963
Synonyms:
KSC-09-140D | KUC105612N | N-benzyl-2-(3-keto-1,2-benzothiazol-2-yl)-N-methyl-acetamide | N-benzyl-N-methyl-2-(3-oxo-1,2-benzothiazol-2-yl)acetamide | N-methyl-2-(3-oxidanylidene-1,2-benzothiazol-2-yl)-N-(phenylmethyl)ethanamide | N-methyl-2-(3-oxo-1,2-benzothiazol-2-yl)-N-(phenylmethyl)acetamide | cid_45256185
Type:
Small organic molecule
Emp. Form.:
C17H16N2O2S
Mol. Mass.:
312.386
SMILES:
CN(Cc1ccccc1)C(=O)Cn1sc2ccccc2c1=O
Structure:
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