Reaction Details Report a problem with these data
Target
Glucose-6-phosphate 1-dehydrogenase
Ligand
BDBM61998
Substrate
n/a
Meas. Tech.
G6DPH counterscreen for TbHK1 inhibitors - Analogues series
IC50
>25000±n/a nM
Citation
 PubChem, PC G6DPH counterscreen for TbHK1 inhibitors - Analogues series PubChem Bioassay (2010)[AID] 
Target
Name:
Glucose-6-phosphate 1-dehydrogenase
Synonyms:
G6PD_LEUME | glucose-6-phosphate dehydrogenase | zwf
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54421.26
Organism:
Leuconostoc mesenteroides
Description:
gi_149631
Residue:
486
Sequence:
MVSEIKTLVTFFGGTGDLAKRKLYPSVFNLYKKGYLQKHFAIVGTARQALNDDEFKQLVRDSIKDFTDDQAQAEAFIEHFSYRAHDVTDAASYAVLKEAIEEAADKFDIDGNRIFYMSVAPRFFGTIAKYLKSEGLLADTGYNRLMIEKPFGTSYDTAAELQNDLENAFDDNQLFRIDHYLGKEMVQNIAALRFGNPIFDAAWNKDYIKNVQVTLSEVLGVEERAGYYDTAGALLDMIQNHTMQIVGWLAMEKPESFTDKDIRAAKNAAFNALKIYDEAEVNKYFVRAQYGAGDSADFKPYLEELDVPADSKNNTFIAGELQFDLPRWEGVPFYVRSGKRLAAKQTRVDIVFKAGTFNFGSEQEAQEAVLSIIIDPKGAIELKLNAKSVEDAFNTRTIDLGWTVSDEDKKNTPEPYERMIHDTMNGDGSNFADWNGVSIAWKFVDAISAVYTADKAPLETYKSGSMGPEASDKLLAANGDAWVFKG
  
Inhibitor
Name:
BDBM61998
Synonyms:
4-fluoranyl-2-[(4-methoxyphenyl)carbonylamino]benzoic acid | 4-fluoro-2-(p-anisoylamino)benzoic acid | 4-fluoro-2-[(4-methoxybenzoyl)amino]benzoic acid | 4-fluoro-2-[[(4-methoxyphenyl)-oxomethyl]amino]benzoic acid | KSC-6-276 | KUC105801N | cid_16785950
Type:
Small organic molecule
Emp. Form.:
C15H12FNO4
Mol. Mass.:
289.2585
SMILES:
COc1ccc(cc1)C(=O)Nc1cc(F)ccc1C(O)=O
Structure:
Search PDB for entries with ligand similarity: